Hot-pe trial

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WebDec 4, 2024 · Much more evidence is expected on short notice, notably for the HOME-PE study. In this randomized controlled noninferiority trial, 1975 normotensive PE patients are randomized to risk stratification by either the Hestia rule or the simplified PESI (sPESI) for determining the possibility of home treatment (#NCT02811237). WebOct 8, 2024 · Ambulatory treatment of low-risk pulmonary embolism in fragile patients: a subgroup analysis of the multinational Home Treatment of Pulmonary Embolism (HoT …

Diagnosis, Treatment and Follow Up of Acute Pulmonary …

WebMar 20, 2024 · HoT-PE 4. Trial design: A prospective, multicenter, single-arm, investigator-initiated, and academically sponsored management trial to investigate the efficacy and … WebAug 31, 2024 · Patients with acute pulmonary embolism can be selected for home management using the sPESI score or the Hestia criteria, according to results of the HOME-PE trial presented in a Hot Line session ... is kefir yoghurt better than greek

Home treatment of fragile patients with acute pulmonary …

WebThieme E-Books & E-Journals. › Author Affiliations Financial support: HoT-PE is an independent, investigator-initiated trial. The study has an academic sponsor (Center for Thrombosis and Hemostasis, University Medical Center Mainz, Germany) and is supported by public funding (German Federal Ministry of Education and Research; BMBF 01E01003). WebSep 27, 2016 · Erratum to Barco et al. "Home treatment of patients with lowrisk pulmonary embolism with the oral factor Xa inhibitor rivaroxaban. Rationale and design of the Hot … WebThe present analysis of the population of HoT-PE, a multinational prospective management trial, support the feasibility and safety of early discharge and home treatment of carefully … is keflex a narcotic

HoT-PE Puts Early Discharge for Low-Risk PE on Front Burner

Oral Rivaroxaban for the Treatment of Symptomatic Pulmonary Embolism

WebAcross trials, 24%–46% of patients with index PE had anatomically extensive PE, 39–41 and 28% of patients with index PE had RVD. 41 Available data in these subgroups, although scarce, suggest that the effect in patients with index PE is consistent regardless of anatomical extension of PE, 34 or presence/absence of RVD. 41 WebJan 21, 2024 · The rationale and study design of HoT-PE have been published previously. 17 HoT-PE (EudraCT Nr. 2013-001657-28) is a prospective multicentre single-arm … keyboards for graphic artistsWebAug 7, 2024 · Aims: The aim of this study is to compare the Hestia rule vs. the simplified Pulmonary Embolism Severity Index (sPESI) for triaging patients with acute pulmonary embolism (PE) for home treatment. keyboards for ipads 6th generation

"WebMay 23, 2024 · The HoT-PE Trial was a prospective multicentre single-arm investigator-initiated Phase 4 interventional trial, in which patients with symptomatic acute PE were … " - Hot-pe trial

Hot-pe trial

Triaging acute pulmonary embolism for home treatment by …

WebSep 18, 2024 · The Home Treatment of Patients with Low-Risk Pulmonary Embolism with the Oral Factor Xa Inhibitor Rivaroxaban (HoT-PE) ... TABLE 2: Early discharge … WebStudy design and participants. HoT-PE (EudraCT identifier 2013-001657-28) is a prospective multicentre single-arm investigator-initiated phase 4 interventional trial sponsored by the University Medical Center Mainz, Mainz, Germany [].The institutional Ethics Review Board of each participating site approved the study and patients provided …

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WebIn a sub-analysis of the Hot-PE trial, although fragile patient population (age >75 years, renal dysfunction [creatinine clearance <50 mL/min], and body mass index <18.5 kg/m 2 ) had higher rate ... WebOct 23, 2024 · What does HOME-PE teach us, also viewed against the background of existing data and particularly those of the recent Home Treatment of Pulmonary Embolism (HoT-PE) 7, 10 trial? Both studies, the main characteristics of which are shown for comparison in Table 1 , yielded excellent results in terms of efficacy and safety of an …

WebMar 1, 2024 · The safety outcome of major bleeding was 1.2% in the Barco et al study and 0.7-1.8% in prior trials with warfarin. In previous trials of rivaroxaban in DVT, the major bleeding rates were 0.5-2.0%. Thus, efficacy and safety are similar to PE trials with warfarin and DVT studies with DOACs. WebMar 31, 2024 · The HoT-PE Study was a prospective, international, multicenter, single-arm, phase 4 management study designed to evaluate whether early discharge and ambulatory treatment with XARELTO is effective and safe in patients with acute low-risk PE. 18, 19. ... Rationale and design of the HoT-PE Trial.

WebMar 24, 2016 · The HoT-PE Trial (home treatment of patients with low-risk PE with the oral factor Xa inhibitor rivaroxaban) is a prospective cohort study enrolling low risk PE … WebThe HoT-PE Trial 3 Male, 81 ≥ 1 Major bleedinga 20 mg once daily 57 12 Haemorrhagic shock following acute bleeding from intestinal diverticula. Red blood cell concentrates; rivaroxaban discontinuation and switch to LMWH. Subsequently, the patient suffered one further gastrointestinal major bleeding episode on heparin.

WebMay 4, 2024 · Embolism (HoT-PE) Trial Running head: Home treatment of low-risk PE in fragile patients Lukas Hobohm, MD1,2, Toni Anušić3, Stavros V Konstantinides, MD1,4, Stefano Barco, MD1,5 for the HoT-PE Investigators 1Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg University, …

WebJan 21, 2024 · Aims: To investigate the efficacy and safety of early transition from hospital to ambulatory treatment in low-risk acute PE, using the oral factor Xa inhibitor rivaroxaban. … is kefir yogurt good for youWebMar 20, 2024 · HoT-PE 4. Trial design: A prospective, multicenter, single-arm, investigator-initiated, and academically sponsored management trial to investigate the efficacy and safety of early transition from hospital to ambulatory treatment in low-risk acute PE (identified through a modified Hestia criteria) in patients taking XARELTO ® (15 mg twice … keyboards for hypotoniaWebJul 4, 2016 · Pulmonary embolism (PE) is a potentially life-threatening acute cardiovascular syndrome. However, ... Rationale and design of the HoT-PE Trial Thromb Haemost. … is kefir yoghurt good for youWebFeb 4, 2024 · Introduction: Early discharge of patients with acute low-risk pulmonary embolism requires validation by prospective trials with clinical and quality-of-life … is keflex and cefazolin the sameWebPulmonary embolism is a common disease, with an estimated annual incidence of 70 cases per 100,000 population. 1,2 The condition usually leads to hospitalization and may recur; it can be fatal. 3 ... is keflex and antibioticWebMar 16, 2024 · Home Treatment of Patients with Low-Risk Pulmonary Embolism with the Oral Factor Xa Inhibitor Rivaroxaban: the HoT-PE Study Posted: 03/16/2024; Author: Stavros Konstantinides, MD; ACC Slide Presentations 2024; keyboards for dell computersWebAug 31, 2024 · Sophia Antipolis, France – 31 Aug 2024: Patients with acute pulmonary embolism can be selected for home management using the sPESI score or the Hestia criteria, according to results of the HOME-PE trial presented in a Hot Line session today at ESC Congress 2024. 1. Principal investigator Professor Pierre-Marie Roy of the … keyboards for computers walmart